Design, build, and deploy agent-based AI systems that improve the quality and reliability of clinical data extraction in production.
Own technical design and delivery for agent workflows.
Integrate new AI capabilities into existing production platforms with attention to performance, scalability, and cost.
Develop evaluation and monitoring approaches to measure impact, guide iteration, and support safe deployment in a regulated environment.
Requirements
Natera is seeking a Senior Agentic AI Engineer to design, build, and productionize intelligent agent workflows that improve the quality, reliability, and efficiency of our Real-World Data (RWD) clinical extraction platform.
This role sits at the intersection of applied AI, software engineering, and healthcare data.
You will extend a live production pipeline that powers RWD delivery, adding modular AI capabilities that improve what source material reaches extraction, how accurately values are extracted from clinical text, and how uncertain or low-confidence outputs are flagged or corrected before they enter RWD datasets. You will work with limited day-to-day direction defining technical approach and delivering measurable improvements through careful evaluation and phased rollout.
Partner with clinical AI, engineering, and product teams to prioritize problems, define success metrics, and ship incremental improvements.
Bachelor’s or Master’s degree in Computer Science, Engineering, or a related technical field; an advanced degree or background in a clinical or life sciences discipline is a plus.
experience in LLM-based systems and multi-step or agent-based LLM workflows — including orchestration, structured outputs, error handling, and integration with downstream systems.
Strong hands-on expertise in Python and modern software engineering practices, including testing, code review, workflow orchestration, and agile delivery in large existing codebases. •
Experience designing and operating AI systems in cloud environments, with AWS strongly preferred;
experience with CI/CD, observability, and production support is expected.
Proven ability to work independently and deliver end-to-end - from technical design through integration and rollout - with strong communication and collaboration across technical and non-technical stakeholders. •
Experience with retrieval-based or document-centric AI systems is strongly preferred. •
Experience in healthcare, life sciences, or other regulated industries is strongly preferred.
Python and Object-Oriented Programming
LLM-Based Systems and Multi-Step or Agent-Based AI Workflows
Retrieval-Based or Document-Centric AI Systems
AWS Services, such as S3, SQS, and Lambda/Fargate
Docker or Container-Oriented Technologies
REST API and Event-Driven Pipeline Architecture Linux Fundamentals CI/CD
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Experience
7+ years of software engineering experience, including substantial work on production systems at scale.
3+ years building and shipping AI/ML-powered applications in production, with hands-on
Benefits
Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other
benefits include pregnancy and baby bonding leave, 401k benefits, commuter
Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY.
Additional details
Our RWD products transform unstructured and semi-structured clinical documents into structured, research- and care-ready datasets that support oncology and broader clinical use cases.
The ideal candidate combines strong hands-on engineering with
experience shipping LLM-powered systems in production. This is a senior individual contributor role with high autonomy and end-to-end ownership from design through deployment. PRIMARY RESPONSIBILITIES
Provide technical leadership through clear documentation, design decisions, and pragmatic tradeoffs across accuracy, cost, and delivery timelines.
Healthcare or Regulated-Industry Data Environments
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
When you join Natera, you’ll work hard and grow quickly.
Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee
benefits and much more. We also offer a generous employee referral program!
Natera is proud to be an Equal Opportunity Employer.