product
Posted Apr 9Lead Product Manager, Clinical Genomics
at Natera
United StatesRemote
Responsibilities
- Define and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectives •
- Influence platform-level technical direction in partnership with engineering leadership •
- Define and evolve end-to-end user workflows, including UI/UX
- Drive cross-team alignment on shared data contracts and workflow standards •
- Mentor and raise the bar for product management within the RIR organization •
- Own measurable improvements in clinical workflow efficiency, reliability, and operational scalability •
- Establish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investments. •
- Develop and track quantitative metrics related to usability, performance, reliability, and adoption •
- Lead delivery teams with clear strategic direction, ensuring
- Proactively identify systemic risks, architectural constraints, and workflow inefficiencies that may limit scale or regulatory robustness, and lead cross-functional initiatives to resolve them •
- Create clear, data-driven written proposals and presentations to support stakeholder alignment and decision-making •
- Track record of independently operating in ambiguous environments and establishing product direction Preferred •
Requirements
- Bachelor’s degree in life sciences, engineering, computer science, statistics, or equivalent experience • 7+ years of
- experience in software product management, including ownership of complex, multi-team or platform-level initiatives • 5+ years
- experience working on production software in healthcare, clinical genomics, or other regulated lifesciences domains, with demonstrated impact on validation, compliance, and system scalability • Demonstrated
- Proven ability to drive alignment across highly matrixed organizations without direct authority
- Experience with clinical genomics and variant processing and interpretation workflows •
- Familiarity working with backend services, APIs, or data-driven systems
- Proven ability to influence without authority and drive alignment across teams •
- Familiarity with Next Generation Sequencing concepts is beneficial
- Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Benefits
- Ability to operate effectively at both tactical and strategic levels, connecting detailed execution to broader platform vision. •
- The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.
- Remote USA $143,200 — $179,000 USD OUR OPPORTUNITY
- Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
- benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other
- benefits include pregnancy and baby bonding leave, 401k benefits, commuter
Contact
- For more information, visit www.natera.com .
- Link: https://www.natera.com/notice-of-data-collection-california-residents/
- Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY.
Additional details
- Natera offers genetic risk assessment and diagnostic tests to patients through medical providers.
- The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant interpretation, clinical review, and reporting.
- As Natera scales across Women’s Health, Oncology, and Organ Health, delivering cohesive, reliable, and compliant software experiences is foundational to clinical quality and commercial success.
- Natera is seeking a Lead Product Manager to define and drive strategy for core components of the Results, Interpretation, and Reporting (RIR) platform.
- This role is responsible for shaping scalable, compliant, and cohesive clinical software systems that support complex genomics workflows across multiple business units.
- The Lead PM will operate as a platform-level owner, ensuring long-term architectural soundness, regulatory robustness, and measurable clinical and operational outcomes.
- The Lead Product Manager will lead cross-functional alignment across engineering, clinical, quality, and downstream systems to ensure RIR components operate as a cohesive, scalable platform.
- This role will identify systemic gaps, resolve cross-team tradeoffs, and drive architectural and workflow decisions that support long-term growth and regulatory compliance.
- This role will initially own one or more RIR software components or initiatives, with responsibility for defining long-term strategy, aligning cross-component workflows, and ensuring scalable architecture across user-facing applications, data contracts, and backend services.
- The Lead PM will drive strategic investment decisions, establish standards for usability and reliability, and ensure systems meet evolving clinical, operational, and regulatory requirements.