Senior Bioinformatics Scientist

United StatesRemote

Responsibilities

Analyze complex genomic datasets leveraging scaled in-house pipelines, partnering cross-functionally with wet-lab scientists and statisticians to rapidly deliver data-driven answers to critical research goals.
Architect, build, and deploy automated analysis pipelines for diagnostic tests, integrating robust capabilities for fusion detection, variant calling, and automated quality control metrics.
Engineer novel genomic analysis tools and proactively identify optimization pathways to enhance pipeline accuracy and efficiency.
Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems.

Natera is seeking a Senior Bioinformatics Scientist to lead the architecture, development, and automation of high-throughput genomic pipelines.
The ideal candidate combines a deep understanding of sequence alignment algorithms with strong object-oriented programming skills to design scalable computational workflows in a fast-paced, mission-driven environment. Primary Responsibilities:
Ph.D. or Master's degree with a minimum of 5 years of professional
experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field.
Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows.
Advanced understanding of data structures, algorithm design, and computational complexity.
Strong software engineering proficiency in Java or C++ within a professional production environment.
Demonstrated scripting capability in Python or Perl for data manipulation, automation, and rapid prototyping.
Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts. Prior
experience working with relational databases, particularly MySQL, is highly desirable.
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.
Remote USA $117,400 — $146,800 USD OUR OPPORTUNITY
Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other
benefits include pregnancy and baby bonding leave, 401k benefits, commuter

For more information, visit www.natera.com .
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY.

This role is responsible for building production-grade software tools to analyze next-generation sequencing (NGS) data including variant calling, fusion detection, and data quality control.
Participate in code reviews, technical documentation, and the continuous improvement of core computational workflows.
Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges.
Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders.
This may differ in other locations due to cost of labor considerations.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
When you join Natera, you’ll work hard and grow quickly.
Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee
benefits and much more. We also offer a generous employee referral program!
Natera is proud to be an Equal Opportunity Employer.