research
Posted May 1Principal Clinical Scientist
at Natera
United StatesRemote
Responsibilities
- Lead Clinical Development & Study Design •
- Lead substantial aspects of MCED clinical studies or multiple studies •
- Drive study design, including objectives, endpoints, eligibility criteria, and schedules of assessments •
- Author and review protocols, ICFs, CRFs, and study documents •
- Drive Data Review & Strategic Insight •
- Lead medical and clinical data review to ensure data quality and integrity •
- Analyze complex datasets to identify trends, risks, and opportunities •
- Lead Cross-Functional Execution •
- Lead cross-functional study teams and coordinate execution across functions •
- Collaborate with Clinical Operations, Biostatistics, Medical Affairs, and Regulatory •
- Influence decisions and align stakeholders across competing priorities •
- Drive Study Performance & Program Value •
- Oversee enrollment, site performance, and key study metrics across studies •
- Identify risks and proactively adjust study-level strategies •
- Prioritize activities across studies to ensure quality, timelines, and program impact •
- Lead development of abstracts, presentations, and manuscripts •
- Support internal decision-making and external evidence generation Required
- Track record of scientific publications and conference presentations Key Competencies •
Requirements
- Advanced degree (PhD, PharmD, MD, or equivalent; MS/RN with experience considered) • 8–12 years of
- experience in clinical research, clinical science, or related field • Strong
- experience leading clinical studies and contributing to study design •
- Experience with clinical data review and interpretation Preferred
- Experience in oncology, diagnostics, or early cancer detection •
- Experience working across multiple studies or programs •
- Ability to lead complex clinical studies or multiple workstreams independently •
- Strong analytical skills with ability to synthesize complex data into decisions •
- Ability to operate effectively in a fast-paced, ambiguous environment
- Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Benefits
- The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.
- Remote USA $187,800 — $234,800 USD OUR OPPORTUNITY
- Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
- benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other
- benefits include pregnancy and baby bonding leave, 401k benefits, commuter
Contact
- For more information, visit www.natera.com .
- Link: https://www.natera.com/notice-of-data-collection-california-residents/
- Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY.
Additional details
- We are seeking a Principal Clinical Scientist to lead execution of key components of clinical development for our multi-cancer early detection (MCED) program.
- This role is central to driving study design, clinical data review, and scientific insights across multiple studies.
- You will serve as a clinical science lead within cross-functional teams – partnering with Clinical Operations, Biostatistics, Medical Affairs, and Regulatory to advance study execution and shape clinical strategy.
- This is a high-impact role for someone who can operate independently, manage complexity across studies, and influence decision-making at the study and program level. PRIMARY RESPONSIBILITIES
- Contribute meaningfully to clinical development strategy and study-level decision-making •
- Contribute to process improvements and development of best practices
- Translate data into actionable insights that inform study and program decisions •
- Partner with safety and medical teams on signal detection and escalation
- Contribute to forecasting, planning, and milestone delivery
- Translate clinical and statistical results into clear scientific narratives •