research
Posted 3 hours agoSenior Bioinformatics Scientist
at Natera
San Carlos, United StatesOn-site
Responsibilities
- Innovate, design, develop, and validate advanced algorithms and statistical models to extract actionable insights from large-scale genomic datasets for early cancer detection.
- Co-architect, implement, and deploy automated analysis workflows for clinical diagnostics, ensuring robust performance for variant calling, fusion detection, and automated quality control.
- Analyze complex multi-omic data using high-performance internal pipelines, collaborating closely with wet-lab scientists and statisticians to meet critical research milestones.
Requirements
- The ideal candidate possesses a robust background in algorithm development, high-throughput biological data analysis, and scalable pipeline architecture.
- PhD in Bioinformatics, Computer Science, Engineering, Statistics, Cancer Biology or similar field
- experience in bioinformatics or computational biology.
- Excellent communication skills with a demonstrated ability to present complex computational findings to diverse cross-functional stakeholders.
- Deep expertise in high-throughput DNA sequencing (NGS) analysis, including sequence alignment, mapping, and clinical-grade variant calling.
- Advanced knowledge of data structures, algorithm design, and computational complexity analysis.
- High proficiency in Python and its scientific ecosystem (NumPy, Pandas, Scikit-learn) for data manipulation and automation. •
- Experience with workflow orchestration languages (WDL preferred) for building and versioning scalable bioinformatics pipelines. •
- Experience with cloud-based distributed computing environments, specifically AWS.
- Familiarity with contemporary analytical techniques and biomarkers in cancer biology.
- Working knowledge of public genomic databases such as TCGA, COSMIC, or OncoKB.
- Proficiency in Linux environments, including command-line tools and shell scripting.
- Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Experience
- 0–3 years of professional or postgraduate
Benefits
- Compensation & Total Rewards
- This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
- This position is also eligible for additional compensation and
- benefits through Natera’s robust Total Rewards program, including: •
- Annual performance incentive bonus •
- Long-term equity awards •
- Comprehensive health benefits (medical, dental, vision) •
- Generous paid time off and company holidays •
- Compensation Range $130,700 — $163,400 USD OUR OPPORTUNITY
- Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
- benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other
- benefits include pregnancy and baby bonding leave, 401k benefits, commuter
Contact
- For more information, visit www.natera.com .
- Link: https://www.natera.com/notice-of-data-collection-california-residents/
- Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY.
Additional details
- As a core member of the Research and Development department, you will play a pivotal role in designing and implementing innovative computational solutions.
- We are looking for a versatile professional capable of thriving as an individual contributor, a collaborative co-developer, and a key participant in large-scale, cross-departmental initiatives.
- In this role, you will develop novel algorithms and pipelines while analyzing complex genomic datasets to advance the frontiers of early-stage cancer diagnostics. PRIMARY RESPONSIBILITIES:
- Contribute to rigorous code reviews, maintain comprehensive technical documentation, and drive the continuous optimization of core computational infrastructure.
- The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.
- When you join Natera, you’ll work hard and grow quickly.
- Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee
- benefits and much more. We also offer a generous employee referral program!
- Natera is proud to be an Equal Opportunity Employer.
- We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives.